Oral Care and Dentistry

Dental Stem Cells

Stem cells are undifferentiated cells, capable of renewing themselves. Via differentiation, they have the potential to develop into many different cell lineages. There are different kinds of stem cells, depending on the type of cells they can create and the location in the body. Dental stem cells (DSCs), an important source of mesenchymal stem cells (MSCs), can be easily obtained by minimally invasive procedures and have been used for the treatment of various diseases. Classic paradigm attributed the mechanism of their therapeutic action to direct cell differentiation after targeted migration, while contemporary insights into indirect paracrine effect opened new avenues for the mystery of their actual low engraftment and differentiation ability in vivo.